Figure 3:
Change in cortical Aβ burden over time in subgroup of 30 older adults who underwent two PET scans (N=19 without remote mTBI or repetitive head impact exposure, N=11 with 1+ remote mTBI). Mixed effects models suggested a possible, but not statistically significant, association (p=.10) of typically aging older adults with remote mTBI (dark blue) having a higher rate of Aβ accumulation over time than those with no remote head trauma (light blue). Bars represent 95% confidence interval of model predicted cortical Aβ burden for each group. Dotted lines show individual participants.