TABLE 2.
Echocardiographic and hemodynamic data of the overall population pre- and post-PMV
| Variablesa | Pre | Post | P value |
|---|---|---|---|
| Echocardiographic data | |||
| LA diameter (mm) | 50.1 ± 6.2 | 48.1 ± 6.7 | <0.001 |
| Mitral peak gradient (mmHg) | 19.9 ± 7.3 | 12.3 ± 4.8 | <0.001 |
| Mitral mean gradient (mmHg) | 11.7 ± 5.1 | 5.7 ± 2.7 | <0.001 |
| Mitral valve area (cm2) | 0.94 ± 0.26 | 1.65 ± 0.23 | <0.001 |
| Hemodynamic data | |||
| LA pressure (mmHg) | 26.2 ± 8.2 | 17.1 ± 5.6 | <0.001 |
| SPAP (mmHg) | 53.2 ± 22.8 | 44.2 ± 14.6 | <0.001 |
| MPAP (mmHg) | 34.1 ± 13.7 | 28.3 ± 9.8 | <0.001 |
| LV end-diastolic pressure (mmHg) | 11.5 ± 3.9 | 13.4 ± 4.2 | <0.001 |
| Cardiac output (L/min) | 3.9 ± 1.2 | 4.1 ± 1.3 | 0.002 |
| Cardiac index (L/min/m2) | 2.4 ± 0.7 | 2.6 ± 0.8 | 0.003 |
| Compliancesb | |||
| Ca (mL/mmHg) | 5.3 [3.2–8.2] | 8.7 [5.3–19.2] | <0.001 |
| Cv (mL/mmHg) | 4.6 [3.2–6.8] | 4.4 [3.1–5.6] | 0.637 |
| Cav (mL/mmHg) | 2.2 [1.6–3.4] | 2.8 [2.1–4.1] | <0.001 |
| Natriuretic peptide | |||
| BNP (pg/mL) | 185 [121–327] | 107 [65–218] | <0.001 |
a
Data are expressed as the mean value ± SD when the data has a normal distribution or as the median [interquartile range] when the data has a non-normal distribution.
b
Including the patients who developed severe mitral regurgitation post PMV.
Abbreviations: Ca, LA compliance; Cav, net left atrioventricular compliance; Cv, left ventricular compliance; LV, left ventricle; MPAP, mean pulmonary artery pressure; SPAP, systolic pulmonary artery pressure.