TABLE 3.
Factors associated with NYHA functional class at follow-upa
| Covariates | Odds ratio | (95% CI) | P value | |
|---|---|---|---|---|
| Univariable analysis | ||||
| Baseline data | Age (years) | 0.96 | 0.93–0.99 | 0.010 |
| Postprocedural data | LA pressure (mmHg) | 1.03 | 0.96–1.10 | 0.387 |
| Transvalvular gradient (mmHg) | 1.06 | 0.94–1.19 | 0.368 | |
| MPAP (mmHg) | 1.01 | 0.97–1.05 | 0.664 | |
| Mitral valve area (cm2) | 4.88 | 0.95–25.07 | 0.058 | |
| Moderate mitral regurgitation | 0.75 | 0.29–1.91 | 0.544 | |
| Changes in the variablesb | Changes in LA pressure (mmHg) | 0.97 | 0.91–1.02 | 0.219 |
| Changes in LA compliance (mL/mmHg) | 1.36 | 1.00–1.85 | 0.045 | |
| Changes in BNP (pg/mL) | 0.48 | 0.22–1.07 | 0.075 | |
| Changes in mitral valve gradient (mmHg) | 0.45 | 0.17–1.20 | 0.110 | |
| Multivariable analysisc | ||||
| Age (years) | 0.95 | 0.92–0.98 | 0.004 | |
| Changes in LA compliance (mL/mmHg) | 1.42 | 1.02–1.97 | 0.037 |
a
Total of 130 patients were included in the analysis, 7 patients were excluded due to severe mitral regurgitation after the procedure
b
Percentage change was calculated using this formula: Post-Pre/Pre × 100%.
c
Multivariable analysis after adjustment for immediate procedural results: postprocedural mitral valve area, MPAP, and mean transvalvular gradient.
Abbreviation: LA, left atrial.