Table 2.

Odds ratio for occurrence of HHV with COVID-19 before and after adjustments for co morbidities

	Odds ratio	95% Wald confidence limits		P value
HSV-1 vs no HSV-1*	5.273	3.541	7.851	<.0001
HSV-1 vs no HSV1	5.185	3.48	7.725	<.0001
Male vs female	0.908	0.795	1.038	0.157
HSV-1 vs no HSV-12	4.487	3.007	6.695	<.0001
Black vs other	3.337	2.788	3.993	<.0001
White vs other	1.271	1.086	1.486	<.0001
HSV-1 vs no HSV-13	4.612	3.095	6.871	<.0001
Age 18–34 vs 0–17	5.85	4.217	8.116	<.0001
Age > 34 vs 0–17	2.936	2.128	4.052	0.0405
HSV-1 vs No HSV-14	1.946	1.283	2.953	0.0017
Respiratory disease vs no respiratory disease	8.635	7.511	9.927	<.0001
HSV-1 vs no HSV-15	3.181	2.174	4.655	<.0001
Endocrine disease vs no endocrine disease	4.264	3.733	4.87	<.0001
HSV-1 vs no HSV-16	1.379	0.758	2.508	0.2919
Obesity vs no obesity	5.705	4.91	6.63	<.0001
HSV-1 vs no HSV-17	3.542	2.269	5.53	<.0001
Diabetes vs no diabetes	3.485	2.887	4.206	<.0001
HSV-1 vs no HSV8	3.77	2.542	5.59	<.0001
Circulatory disease vs no circulatory disease	3.01	2.624	3.453	<.0001
HSV-1 vs no HSV-19	5.101	3.339	7.793	<.0001
Smokers vs never smoked	0.976	0.822	1.158	0.7772
VZV vs no VZV*	5.266	3.105	8.931	<.0001
VZV vs no VZV1	5.2	3.064	8.825	<.0001
Male vs female	0.886	0.776	1.012	0.0756
VZV vs no VZV2	5.476	3.224	9.302	<.0001
Age 18–34 vs 0–17	5.475	3.988	7.517	<.0001
Age > 34 vs 0–17	2.635	1.929	3.6	0.2
VZV vs no VZV3	4.76	2.803	8.084	<.0001
Black vs other	3.679	3.071	4.406	<.0001
White vs other	1.34	1.142	1.572	<.0001
VZV vs no VZV4	1.341	0.694	2.591	0.383
Respiratory disease vs no respiratory disease	8.542	7.436	9.813	<.0001
VZV vs VZV5	2.233	1.286	3.876	0.0043
Endocrine disease vs no endocrine disease	4.247	3.719	4.849	<.0001
VZV vs no VZV6	1.484	0.703	3.13	0.3002
Obesity vs no obesity	5.556	4.778	6.46	<.0001
VZV vs no VZV7	2.336	1.205	4.528	0.012
Diabetes vs no diabetes	3.42	2.827	4.138	<.0001
VZV vs no VZV8	2.851	1.673	4.858	0.0001
Circulatory disease vs no circulatory disease	3.091	2.696	3.544	<.0001
VZV vs no VZV9	2.616	1.506	4.544	0.0006
Neurological disease vs no neurological disease	3.43	2.996	3.928	<.0001

^*Raw models that evaluate the association between COVID-19 status with herpes and herpes zoster without adjusting for any covariate

¹Adjusts for gender

²Adjusts for race

³Adjusts for age

⁴Adjusts for respiratory disease

⁵Adjusts for endocrine disease

⁶Adjusts for obesity

⁷Adjusts for diabetes

⁸Adjusts for circulatory disease

⁹Adjust for smoking and neurological disease