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. 2021 Jul 11;22:40. doi: 10.1186/s40360-021-00505-x

Table 5.

Mixed Effects Model Regressions

Parameters Model Parameters
Instrumental Variable Parameter Estimate (C.I.) P-Value S.D. R-Squared Wald ChiSqu. dF P
ivreg(TestCa ~ Race)
Race_Asian 0.26 (−25.24, 25.77) 0.984 132.073 0.8888 2463 3921 < 2.2E-16
Race_Hispanic 2.7 (−13.73, 19.12) 0.748
Race_NHWhite 3.5 (−12.93, 19.92) 0.677
ivreg(TestCa ~ Ethnic_THC_Exposure)
Ethnic_THC_Exp 0.89 (0.88, 0.91) << 2.3E-320 102.3782 0.9332 1.29E+ 04 1923 << 2.3E-320
ivreg(Rate ~ Ethn_THC_Exposure + Race)
Ethn_THC_Exposure: NHCaucasian-Am._THC_Exposure 0.08 (0.02, 0.13) 0.0095 8.4472 0.0361 29.06 64,493 << 1.0E-320
Ethn_THC_Exposure: NHAfrican-Am._THC_Exposure −0.09 (−0.14, −0.03) 0.0032
Ethn_THC_Exposure: NHPI_THC_Exposure −0.19 (− 0.25, − 0.13) 3.4E-09
Ethn_THC_Exposure: Hispanic-Am._THC_Exposure −0.25 (− 0.32, − 0.18) 4.2E-13
Ethn_THC_Exposure: Asian-Am._THC_Exposure − 0.63 (− 0.74, − 0.52) 3.6E-29
Ethnic_THC_Exp − 0.35 (− 0.4, − 0.3) 1.5E-38
ivreg(TestCaRt ~ log(EthnTHCExp) * Race)
NHWhite: Ethn_THC_Exp 1.22 (1.16, 1.27) 6.9E−128 95.9894 0.9430 3703 4920 < 2e-16
Hispanic: Ethn_THC_Exp 1.48 (1.38, 1.59) 5.6E-214
ivreg(TestCaRt ~ log(EthnTHCExp) * Race)
THC RaceAsian 3.88E+ 05 (−8.93E+ 07, 9.01E+ 07) 0.993 130,195 -1.1E-05 9.013E+ 05 3921 1.0000
Cannabigerol RaceHispanic 1.47E+ 05 (−3.38E+ 07, 3.40E+ 07) 0.993
Cannabinol RaceNHWhite 1.47E+ 05 (− 3.38E+ 07, 3.41E+ 07) 0.993
ivreg(TestCa ~ Cigarettes * AUD * Ethn_THC_Exposure + Race + Cocaine + MHY + Analgesics)
AUD 138.37 (126.96, 149.78) < 2e-16 24.2846 0.9962 2.04E+ 04 12,912 < 2.2E-16
AUD: Ethnic_THC_Exp 312.53 (290.54, 334.53) < 2e-16
Cigarettes: Ethnic_THC_Exp 150.41 (139.67, 161.15) < 2e-16
Analgesics 1.07 (0.67, 1.47) 1.8E-07
NHCaucasian-Am. 3.25 (0.22, 6.28) 0.0361
Hispanic-Am. 2.91 (−0.12, 5.93) 0.0597
Cocaine − 132.56 (−150.11, −115.01) < 2e-16
Cigarettes −45.52 (−50.67, −40.37) < 2e-16
Ethnic_THC_Exp −22.08 (−24, −20.17) < 2e-16
MHY −12.03 (− 12.98, − 11.08) < 2e-16
Cigarettes: AUD: Ethnic_THC_Exp − 2032.86 (− 2169.16, − 1896.55) < 2e-16
ivreg(TestCa ~ Cigarettes * AUD * Ethnic_THC_Exp * Race + Cocaine + MHY + Analgesics)
THC Cigarettes 30.94 (21.36, 40.52) 3.9E-10 16.2755 0.0138 20.04 3921 1.37E-12
Cannabigerol Ethnic_THC_Exp 0.55 (0.05, 1.05) 0.0298
Cannabinol AUD −49.84 (−64.89, −34.78) 1.4E-10
ivreg(Rate ~ Cigarettes * AUD + Analgesics + Cocaine + MHY + Race * Ethnic_THC_Exposure)
Cocaine 61.73 (56.9, 66.56) 6.1E-130 6.8060 0.3801 173.4 16,4483 << 1.0E-320
Cigarettes: AUD 142.1 (126.47, 157.73) 5.2E-69
NHPI 0.52 (0.34, 0.7) 1.8E-08
Ethnic_THC_Exp 0.32 (0.2, 0.43) 4.7E-08
Asian-Am. 0.44 (0.25, 0.63) 6.8E-06
Hispanic-Am. 0.24 (0.06, 0.42) 0.00752
Asian-Am.: Ethnic_THC_Exp −0.41 (−0.56, −0.26) 1.68E-07
NHPI: Ethnic_THC_Exp −0.37 (− 0.5, − 0.24) 2.96E-08
Analgesics −1.13 (−1.29, − 0.97) 7.65E-44
Cigarettes −38.49 (−42.35, −34.63) 3.90E-82
MHY −9.58 (−10.06, −9.1) 4.1E-289