Table 1.
Time post-inoculation, pulmonary bacterial counts and TNF-α correlate to the lung microbiota over time
| p-value | F model | R2 | |
|---|---|---|---|
| Murine gender | 0.689 | 0.420 | 0.006 |
| CFU in blood | 0.876 | 0.765 | 0.399 |
| MCP-1 | 0.618 | 0.830 | 0.966 |
| IFN-y | 0.220 | 1.183 | 0.317 |
| IL-6 | 0.191 | 1.590 | 0.936 |
| TNF-α | 0.044 | 1.877 | 0.875 |
| CFU in lung | 0.008 | 2.263 | 0.852 |
| Time post-inoculation | 0.001 | 15.905 | 0.546 |
Values were calculated using Permanova and used ASV level data for the lung microbiota, the cytokines were measured in lung homogenates
ASV amplicon sequence variance, CFU colony forming unit, MCP-1 monocyte chemoattractant protein 1, IFN-γ interferon γ, IL-6 Interleukin 6 and TNF-α tumor necrosis factor α