Fig. 4.
a An 11.5-year-old girl with osteogenesis imperfecta (OI) type III and dentinogenesis imperfecta (DGI; patient no. 10). Enamel hypoplasia is visible on the lower left premolar. All premolars in the upper jaw, along with the second premolars in the lower jaw, are congenitally missing. BP treatment began when the girl was 0.29 years old. b A 19-year-old man with OI type IV and DGI (a control) who has received BP therapy from the age of 17 years. No enamel disturbances are visible