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. 2021 Mar 20;109(2):121–131. doi: 10.1007/s00223-021-00835-2

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a An 11.5-year-old girl with osteogenesis imperfecta (OI) type III and dentinogenesis imperfecta (DGI; patient no. 10). Enamel hypoplasia is visible on the lower left premolar. All premolars in the upper jaw, along with the second premolars in the lower jaw, are congenitally missing. BP treatment began when the girl was 0.29 years old. b A 19-year-old man with OI type IV and DGI (a control) who has received BP therapy from the age of 17 years. No enamel disturbances are visible