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. Author manuscript; available in PMC: 2022 Jan 1.
Published in final edited form as: Nat Genet. 2021 Jul 1;53(7):1006–1021. doi: 10.1038/s41588-021-00886-z

Extended Data Fig. 5. Effects of SPTBN1 variants on dendrites.

Extended Data Fig. 5

a, Images of DIV18 βII-SpWT, βII-SpHet, βII-SpKO, and GFP-βIISp rescued βII-SpKO neurons stained with an anti-GFP antibody. Scale bar, 30 μm. b,c, Quantification of length of primary dendrites (b) and of total number of primary and secondary dendrites (c) of βII-SpWT, βII-SpHet, βII-SpKO, and rescued βII-SpKO DIV18 neurons (n = 6–16 neurons/genotype) compiled from three independent experiments. Data represent mean ± SEM. One-way ANOVA with Dunnett’s post hoc analysis test for multiple comparisons, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. See statistics summary in Source Data Extended Data Figure 5.