Table 8.
MICs of Z-Tyr-Val-OH peptide determined for Gram positive and Gram negative strains.
| Microorganism | MICs* | ||
|---|---|---|---|
| Z-Tyr-Val-OH (μg/ml) | Oxacillin (μg/ml) | Nalidixic acid (μg/ml) | |
| Gram positive bacteria | |||
| Staphylococcus aureus ATCC 25923 | 47.5 ± 0.01b | 31.1 (47) | |
| Staphylococcus aureus C00195 | 96.0 ± 0.00a | ||
| Staphylococcus hominis A17771 | 96.0 ± 0.05a | ||
| Enterococcus faecalis I00125 (MDR) | — | ||
| Gram negative bacteria | |||
| Escherichia coli ATCC 25922 | 55.0 ± 0.01a | 21.7 (48) | |
| Escherichia coli A17683 | 123.0 ± 0.10b | ||
| Klebsiella oxytoca A19438 (SDR) | 140.0 ± 0.05c | ||
| Pseudomonas aeruginosa C00213 (SDR) | — | ||
*
MICs data are representative of three independent experiments which were done in duplicate. MDR, multidrug resistance; SDR, single-drug resistance. The values with different superscript letters in a column are significantly different (p < 0.05) (IBM SPSS Statistics 27.0).