Skip to main content
. 2021 Jun 28;12:694653. doi: 10.3389/fneur.2021.694653

Table 2.

Phenotypes in cerebellar tremors.

Type of cerebellar tremor Phenomenology Responsible region
Kinetic tremor in Holmes' classic study • Irregular and discontinuous sways
• Sometimes marked at the beginning of the movement
The cerebellum (probably destruction of the cerebellar cortex and/or the white matter)
Static tremor in Holmes' classic study • Subtype 1: Irregular oscillation in the extension of upper limbs during the maintenance of the limb against gravity
• Subtype II: Regular oscillations of a limb or some of its segments during maintenance of the limb accurately in certain positions
The cerebellum (probably destruction of the cerebellar cortex and/or the white matter)
Intention tremor • Amplitude increase during visually guided movements toward a target at the movement termination The dentato-rubro-thalamic tract
“Holmes' tremor” • Concomitant expression of rest tremor* and intention tremor with/without postural tremor*
• Slow frequency, usually <4.5 Hz
• Late onset of pathologies
Superior peduncle, midbrain tegmentum, and posterior thalamus
Palatal tremor • Rhythmic movements of the soft palate
• Late onset of pathologies
The brainstem and the cerebellum
Essential tremor • Bilateral, largely symmetric postural tremor or kinetic tremor*
• Involving hands and forearm, with or without head tremor and tremor in other locations
Cerebellar cortex

Kinetic tremor, tremor occurring during any voluntary movement; postural tremor, tremor present while voluntarily maintaining a position against gravity; rest tremor, tremor that occurs in a body part that is not voluntarily activated and is completely supported against gravity.

*

Definition by Consensus Statement of the Movement Disorder Society on Tremor (11).