| Hand eczema-specific medical history |
Duration, recurrence, exposure, etc. |
| Past medical history |
Atopic, endocrine, autoimmune disorders, etc. |
| Exposure history |
Work, hobbies, daily life |
| Family history |
Atopic diathesis |
| To differentiate familial disorders, such as familial palmoplantar keratoderma |
| Physical examination |
Location, morphology, etc. |
| Presence of skin lesions on areas other than hands |
|
| Patch test |
To identify contact allergen |
| When lesions are unresponsive to standard treatment |
| Serum total Immunoglobulin E level |
With atopic diathesis (atopic dermatitis, asthma) |
| When suspicious of allergen sensitization and type 1 hypersensitivity |
| Microbial tests (bacterial, fungal, viral, and helminth) |
When infectious cause is suspected |
| When lesions are unresponsive to standard treatment |
| Skin biopsy |
To differentiate other skin disorders involving palms, such as psoriasis and palmoplantar pustulosis |
| When lesions are unresponsive to standard treatment |
