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. 2021 Jul 1;33(4):333–338. doi: 10.5021/ad.2021.33.4.333

Table 3. Relationship between special staining results and clinical factors.

Variable Mast cell proliferation Neural hyperplasia Merkel cell hyperplasia
Giemsa positive p-value Odds ratio S-100 positive p-value NSE positive p-value CK-20 positive p-value CAM 5.2 positive p-value CK8 and CK18 positive p-value
Atopic dermatitis (n=209) 17 0.0280* 0.0347* 32 0.9088 57 0.6651 2 0.6377 37 0.9097 90 0.8323
Present (n=126) 6 (35.3) 19 (59.4) 33 (57.9) 1 (50.0) 22 (59.5) 55 (61.1)
Not present (n=83) 11 (64.7) 13 (40.6) 24 (42.1) 1 (50.0) 15 (40.5) 35 (38.9)
Treatment response (n=209) 17 0.7742 32 0.1619 57 0.8565 2 0.1048 37 0.7099 90 0.4962
Improved (n=68) 5 (29.4) 7 (21.9) 18 (31.6) 2 (100) 13 (35.1) 27 (30.0)
Non improved (n=141) 12 (70.6) 25 (78.1) 39 (68.4) 0 (0) 24 (64.9) 63 (70.0
Treatment response (n=134) 13 0.3512 19 0.1907 35 0.9252 2 0.4964 24 0.7114 58 0.3962
Improved (n=68) 5 (38.5) 7 (36.8) 18 (51.4) 2 (100) 13 (54.2) 27 (46.6)
Non improved (n=66) 8 (61.5) 12 (63.2) 17 (48.6) 0 (0) 11 (45.8) 31 (53.4)

Values are presented as number only or number (%). NSE: neuron-Specific Enolase, CK: cytokeratin. *Statistically significant (p<0.05).