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Antigen cross-presentation and T-cell priming. (A) Dendritic cell primes CD8+ T cells. Primed CD8+ cells are differentiated into cytotoxic T cells producing perforins and granzymes. (B) DC primes CD4+ T cells. Primed CD4+ cells are differentiated into T helper cells, which in turn activate B cells and differentiate them into memory cells and antibody-producing plasma cells.
