SCHEME 1.

Synthesis of major intermediate 11. aReagents and Conditions. a. Br2/MeOH, Na2CO3 (Yield: 77%); b. Amberlyst‐15, H2O, Acetone (Yield: 72%); c. CH2Cl2 (Yield: 45%); d. Amberlyst‐15, H2O, Acetone (Yield: 42–65%)

Synthesis of major intermediate 11. aReagents and Conditions. a. Br2/MeOH, Na2CO3 (Yield: 77%); b. Amberlyst‐15, H2O, Acetone (Yield: 72%); c. CH2Cl2 (Yield: 45%); d. Amberlyst‐15, H2O, Acetone (Yield: 42–65%)