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. 2021 Jun 28;12:653349. doi: 10.3389/fphys.2021.653349

FIGURE 2.

FIGURE 2

Effect of T89 on myocardial histology, ultrastructure, and myocardial injury after ISO. (A) Representative HE-stained images in Sham (A1, A6), Sham + T89 167.4 group (A2, A7), ISO (A3, A8), ISO + T89 111.6 (A4, A9), and ISO + T89 167.4 (A5, A10). The upper panel was acquired at ×10 magnification of objective, and the lower panel was captured at ×20 magnification of objective. Bar = 100 μm. (B) Representative images of myocardial ultrastructure in Sham (B1), Sham + T89 167.4 group (B2), ISO (B3), ISO + T89 111.6 (B4), and ISO + T89 167.4 (B5). (CE) The alteration of CK MB (C, n = 6) and cTnI (D, n = 6) content in plasma, and ANP content (E, n = 12) in the left ventricle. *P < 0.05 vs. Sham group, #P < 0.05 vs. ISO group.