Table 1.
Demographics of patients receiving 4F-PCC in the emergency department during the study period
| Demographics | Value |
|---|---|
| No. of patients | 184 |
| Age (yr) | 72 ± 17 |
| Sex, male | 109 (59) |
| Sex, female | 75 (41) |
| Selected concomitant medications | |
| Warfarin | 131 (71) |
| Aspirin | 81 (44) |
| Direct oral anticoagulants | 28 (15) |
| Clopidogrel | 17 (9) |
| Not on anticoagulant prior to 4F-PCC administration | 24 (13) |
| Indications for anticoagulation | |
| Atrial fibrillation | 116 (63) |
| Deep venous thrombosis | 29 (16) |
| Venous thromboembolism prophylaxis | 15 (8) |
| Pulmonary embolism | 12 (7) |
| Mitral valve replacement | 6 (3) |
| Site of bleeding | |
| Intracranial | 53 (29) |
| Lower gastrointestinal | 28 (15) |
| Upper gastrointestinal | 19 (10) |
| Retroperitoneal | 7 (4) |
| Hemothorax | 6 (3) |
| Extremities | 4 (2) |
| Abdominal | 6 (3) |
| Pelvic | 4 (2) |
| Epistaxis | 4 (2) |
| Concomitant treatments for bleeding | |
| Vitamin K | 107 (58) |
| Packed red blood cells | 92 (50) |
| Fresh frozen plasma | 70 (38) |
| Platelets | 48 (26) |
| Cryoprecipitate | 15 (8) |
| Factor VII | 4 (2) |
| Factor IX | 1 (1) |
| Interventions | |
| Surgery | 50 (27) |
| Interventional radiology | 16 (9) |
Values are presented as mean±standard deviation or number (%) unless otherwise indicated.
4F-PCC, 4-factor prothrombin complex concentrate.