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. 2021 Jul 5;14:3077–3088. doi: 10.2147/DMSO.S311725

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© 2021 Guo et al.

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MiR-494-3p and miR-574-5p are regulators of C7. (A) and (B) The heatmap and volcano plot of differentially expressed miRNAs. (C) The common miRNAs compared with miRNAs predicted by Targetscan and miRwalk. (D) The relative expression of C7 and different miRNAs in MES cell treated with different glucose. (E) The relative C7 expression in DN cell treated with miR-494-3p mimics and miR-574-5p mimics. (F) Detection of the binding of miR-494-3p and miR-574-5p with C7 by luciferase reporter gene assay. *p < 0.05, **p< 0.001.

Abbreviation: N.S., no significant.