Table 2.
Patient characteristics | No. of patients with grade ≤ 1 pneumonitis | No. of patients with grade ≥ 2 pneumonitis | p value | |
---|---|---|---|---|
Age | ≥ 68 years old | 11 | 4 | 0.742 |
< 68 years old | 11 | 3 | ||
Sex | Female | 19 | 5 | 0.362 |
Male | 3 | 2 | ||
Performance status | 0 | 8 | 1 | 0.271 |
1–3 | 14 | 6 | ||
ICI | Pembrolizmab | 13 | 4 | 0.996 |
Nivolumab | 6 | 2 | ||
Atezolizmab | 3 | 1 | ||
Interval between RT and ICI | ≥ 25 days | 12 | 3 | 0.590 |
< 25 days | 10 | 4 | ||
History of ICI before RT | Yes | 8 | 4 | 0.331 |
No | 14 | 3 | ||
Obstructive pneumonia | Yes | 6 | 5 | 0.036 |
No | 16 | 2 |
ICI: immune checkpoint inhibitors; RT: radiotherapy.