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. 2021 Jun 12;62(4):669–675. doi: 10.1093/jrr/rrab051

Table 2.

Patient factors related to grade ≥ 2 radiation pneumonitis (chi-square test)

Patient characteristics No. of patients with grade ≤ 1 pneumonitis No. of patients with grade ≥ 2 pneumonitis p value
Age ≥ 68 years old 11 4 0.742
< 68 years old 11 3
Sex Female 19 5 0.362
Male 3 2
Performance status 0 8 1 0.271
1–3 14 6
ICI Pembrolizmab 13 4 0.996
Nivolumab 6 2
Atezolizmab 3 1
Interval between RT and ICI ≥ 25 days 12 3 0.590
< 25 days 10 4
History of ICI before RT Yes 8 4 0.331
No 14 3
Obstructive pneumonia Yes 6 5 0.036
No 16 2

ICI: immune checkpoint inhibitors; RT: radiotherapy.