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. 2021 Jun 28;13:672535. doi: 10.3389/fnagi.2021.672535

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Copyright © 2021 Boutzoukas, O'Shea, Albizu, Evangelista, Hausman, Kraft, Van Etten, Bharadwaj, Smith, Song, Porges, Hishaw, DeKosky, Wu, Marsiske, Alexander, Cohen and Woods.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Region-Specific WMH ROIs significant for (A–C) dimensional change card sort test and (D) Flanker inhibitory control and attention test. Partial regression scatter plots for relationships between NIHTB DCCS and Flanker performance and significant Desikan-Killiany frontal regions WMH load for (A) left hemisphere superior frontal, (B,D) right hemisphere superior frontal, (C) right hemisphere medial orbitofrontal.