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. 2021 Jun 28;12:675377. doi: 10.3389/fphys.2021.675377

Schematic 1.

Schematic 1

Schematic representation of the experimental protocol condition in air temperature 25.0 ± 0.5°C and relative humidity 60.0 ± 3.0%. Heat stimulation entailed immersing half of the body into a hot water bath (42 ± 0.5°C) for total 30 min and break for total 30 min. Blood sampling was done before immersion (Pre) and immediately after the last break (Post). Tympanic and local skin temperature measurements were conducted continuously at 10-s intervals for 60 min.