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. 2021 Jul 7;13:11795735211029114. doi: 10.1177/11795735211029114

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© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 4. — Relationship between HO-1, LEDD and HY stage. Disease progression measured by H&Y scale progression. A) HO-1 protein levels of all non-PD controls (n=232) relative to PD cases subdivided into their h&Y stage (HY1 n=18, HY2 n=24, HY3 n=28) and B) HO-1 protein levels and c) LEDD levels among PD patients (n=70) subdivided into their H&Y stage. Statistical analyses were conducted with a=0.05, error bars indicate the mean with SEm. D) Linear regression analysis of LEDD and salivary HO-1 and Pearson correlation.