Table 3.
PD v. | Neurodegenerative conditions v. | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Non-neurological control | Degenerative neurological control | Non-degenerative neurological control | Non-neurodegenerative control | ||||||||||
Univariate logistic regression model | |||||||||||||
Predictor | OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | |
HO-1 (ng/ml) | 1.01 | 1.00−1.03 | .02 | 1 | 0.98−1.01 | .63 | 1.03 | 1.01−1.04 | <.01 | 1.02 | 1.01−1.03 | <.01 | |
Multivariate logistic regression model | |||||||||||||
Predictor | OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | OR | 95% CI | P value | |
HO-1 (ng/ml) | 1.02 | 1.00−1.03 | .01 | 1.00 | 0.97−1.02 | .75 | 1.04 | 1.01−1.07 | <.01 | 1.02 | 1.01−1.03 | <.01 | |
Total protein (mg/ml) | 1.56 | 1.27−1.97 | <.01 | 1.25 | 0.94−1.70 | .13 | 1.34 | 0.97−1.93 | .10 | 1.39 | 1.15−1.68 | <.01 | |
Age (per year) | 1.06 | 1.03−1.10 | <.01 | 0.89 | 0.82−0.94 | <.01 | 1.08 | 1.03−1.15 | <.01 | 1.11 | 1.08−1.15 | <.01 | |
Sex | Female | 1 | (reference) | 1 | (reference) | 1 | (reference) | 1 | (reference) | ||||
Male | 6.45 | 2.94−15.24 | <.01 | 10.45 | 3.36−38.14 | <.01 | 15.35 | 4.27−69.09 | <.01 | 3.27 | 1.75−6.25 | <.01 | |
Arthritis | No | 1 | (reference) | 1 | (reference) | 1 | (reference) | 1 | (reference) | ||||
Yes | 1.15 | 0.52−2.52 | .73 | 2.91 | 1.01−9.16 | .06 | 1.00 | 0.28−3.78 | 1.00 | 0.87 | 0.45−1.66 | .66 | |
Thyroid condition | No | 1 | (reference) | 1 | (reference) | 1 | (reference) | 1 | (reference) | ||||
Yes | 2.02 | 0.77−5.38 | .16 | 14.31 | 2.91−95.60 | <.01 | 1.75 | 0.40−8.75 | .47 | 0.87 | 0.39−1.92 | .73 | |
Cardiac condition | No | 1 | (reference) | 1 | (reference) | 1 | (reference) | 1 | (reference) | ||||
Yes | 1.89 | 0.65−5.56 | .24 | 0.99 | 0.28−3.68 | .99 | 1.19 | 0.24−7.29 | .84 | 2.57 | 1.10−6.24 | .03 | |
Diabetes | No | 1 | (reference) | 1 | (reference) | 1 | (reference) | 1 | (reference) | ||||
Yes | 0.21 | 0.05−0.73 | .02 | 0.08 | 0.01−0.39 | <.01 | 0.54 | 0.05−5.70 | .61 | 0.62 | 0.23−1.60 | .33 |
Abbreviations: OR, odds ratio; 95% CI, 95% confidence interval.