Table 1. Solubility Data for Each Coformer in Water, MeOH, MeCN, EtOAc, and MEK.
compound name | water (mg/mL) | MeOH (mg/mL) | MeCN (mg/mL) | EtOAc (mg/mL) |
---|---|---|---|---|
benzoic acid | <1.0 | 306.4 | 81.5 | 175.0 |
trans-1,2-bis(4-pyridyl)ethylene | <1.0 | 289.0 | <1.0 | <1.0 |
4,4′-bipyridine | 1.8 | 456.7 | 84.1 | 134.6 |
glutaric acid | 570.0 | 458.0 | 99.5 | 602.2 |
1,2-bis(4-pyridyl)ethane | <1.0 | 426.6 | 115.7 | 67.1 |
4,4′-biphenol | <1.0 | 57.1 | 13.3 | 56.1 |
tetramethylpyrazine | <1.0 | <1.0 | <1.0 | <1.0 |
isophthalic acid | <1.0 | 10.8 | 2.0 | 3.4 |
trimesic acid | <1.0 | <1.0 | <1.0 | 1.8 |
hydroquinone | 72.9 | 269.6 | 100.8 | 165.1 |
naproxen | <1.0 | 53.6 | 36.7 | 50.5 |
benzoquinone | 1.8 | 4.8 | 15.2 | 57.7 |
carbamazepine | <1.0 | 63.4 | 43.5 | 12.7 |
4-aminobenzoic acid | 2.7 | 146.9 | 57.9 | 75.5 |
oxalic acid | 85.3 | 190.3 | 110.6 | 96.8 |
aspirin | 2.0 | 221.8 | 63.3 | 25.4 |
1-naphthol | 2.7 | 197.0 | 71.3 | 61.2 |
terephthalaldehyde | <1.0 | 221.5 | 76.2 | 79.7 |
saccharin | 2.9 | 36.4 | 28.2 | 30.2 |
nicotinamide | 419.1 | 180.2 | 21.2 | 10.8 |
2,7-dihydroxynaphthalene | 4.5 | 379 | 76.2 | 79.7 |
resorcinol | 566.5 | 544.4 | 525.8 | 443.5 |
2,6-pyridinecarboxylic acid | 4.0 | 22.9 | <1.0 | <1.0 |