Table 3.
Comparison of Pregnancy Outcomes with and without PASD in Patients with PPCS and Non-PPCS
| Maternal/Neonatal Outcomes | All (n=726) | P-value | With PASD (n=144) | P-value | Without PASD (n=582) | P -value | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| PPCS (n=154) | Non-PPCS (n=572) | PPCS (n=72) | Non-PPCS (n=72) | PPCS (n=82) | Non-PPCS (n=500) | |||||
| Maternal | ||||||||||
| Gestational weeks | 0.019* | 0.630 | 0.315 | |||||||
| 28–36 | 102(67.5) | 312(54.8) | 53(74.6) | 48(67.6) | 49(61.3) | 264(53.0) | ||||
| 37–39 | 46(30.5) | 240(42.2) | 16(22.5) | 21(29.6) | 30(37.5) | 219(44.0) | ||||
| > 40 | 3(2.0) | 17(3.0) | 2(2.8) | 2(2.8) | 1(1.3) | 15(3.0) | ||||
| Mode of delivery | 0.050* | - | 0.125 | |||||||
| Vaginal | 0 | 14(2.4) | 0 | 0 | 0 | 14(2.8) | ||||
| Cesarean section | 154(100.0) | 558(97.6) | 79(100.0) | 72(100.0) | 87(100.0) | 486(97.2) | ||||
| Intraoperative blood loss> 1000 mL | 120(77.9) | 91(16.0) | <0.001* | 65(90.3) | 29(40.8) | <0.001* | 55(67.1) | 62(12.5) | <0.001* | |
| Intraoperative blood loss> 3000 mL | 46(29.9) | 17(3.0) | <0.001* | 38(52.8) | 12(16.9) | <0.001* | 8(9.8) | 5(1.0) | <0.001* | |
| Bleeding within 2 hours after delivery, mL | 34.7±89.7 | 28.5±58.8 | 0.353 | 44.4±113.1 | 19.9±44.6 | 0.109 | 25.6±59.7 | 29.8±60.5 | 0.607 | |
| Bleeding within 2–24 hours after delivery, mL | 168.2±370.1 | 49.9±58.4 | <0.001* | 220.1±436.4 | 65.5±114.2 | 0.007* | 118.9±289.9 | 47.7±45.1 | <0.001* | |
| Postpartum hemorrhage | 75(48.7) | 90(15.7) | <0.001* | 19(26.4) | 14(19.4) | 0.322 | 56(68.3) | 76(15.2) | <0.001* | |
| Transfusion | 53(34.6) | 92(16.1) | <0.001* | 28(39.4) | 24(33.3) | 0.448 | 25(30.5) | 68(13.6) | <0.001* | |
| Hemorrhagic shock | 12(7.8) | 11(1.9) | <0.001* | 10(13.9) | 4(5.6) | 0.091 | 2(2.4) | 7(1.4) | 0.480 | |
| Postpartum anemia | 39(23.5) | 172(30.1) | 0.250 | 19(26.4) | 30(41.7) | 0.053 | 20(24.4) | 142(28.4) | 0.453 | |
| Hysterectomy | 4(2.6) | 3(0.5) | 0.019* | 4(5.6) | 2(2.8) | 0.404 | 0 | 1(0.2) | 0.685 | |
| Neonatal | ||||||||||
| Infant weight, g | 0.916 | 0.616 | 0.826 | |||||||
| <1500 | 6(3.9) | 23(4.1) | 2(2.8) | 1(1.4) | 4(4.9) | 22(4.4) | ||||
| 1500–2500 | 35(22.9) | 145(25.6) | 17(21.8) | 21(29.6) | 18(22.0) | 124(25.0) | ||||
| 2500–4000 | 111(72.5) | 396(69.8) | 51(71.8) | 49(69.0) | 60(73.2) | 347(70.0) | ||||
| >4000 | 1(0.7) | 3(0.5) | 1(1.3) | 0 | 0 | 3(0.6) | ||||
| Intrauterine death | 0(0) | 4(0.7) | 0.298 | 0(0) | 0(0) | - | 0 | 4(0.8) | 0.416 | |
| Fetal distress | 55(35.7) | 69(12.1) | <0.001* | 26(36.1) | 13(18.1) | 0.015* | 29(35.4) | 56(11.2) | <0.001* | |
| Umbilical cord blood pH | 7.17±0.78 | 7.25±0.45 | 0.212 | 7.24±0.12 | 7.26±0.10 | 0.442 | 7.12±1.00 | 7.25±0.48 | 0.157 | |
| APGAR <7at 1 min | 23(15.2) | 40(7.1) | 0.002* | 17(24.6) | 9(12.9) | 0.075 | 6(7.3) | 31(6.3) | 0.715 | |
| APGAR <7at 5 min | 4(2.6) | 16(2.8) | 0.877 | 1(1.4) | 1(1.4) | 0.992 | 3(3.7) | 15(3.0) | 0.769 | |
Notes: Data are mean±SD (independent t-test) or n (%) (x2 test) or Fisher’s Exact Test.; *P < 0.05. Percentages do not total 100% owing to missing data.
Abbreviations: n, number of observations; SD, standard deviation; PASD, placenta accreta spectrum disorder; PPCS, placenta previa with coverage of a uterine scar.