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. 2021 Jun 18;15:641600. doi: 10.3389/fninf.2021.641600

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Copyright © 2021 Boutinaud, Tsuchida, Laurent, Adonias, Hanifehlou, Nozais, Verrecchia, Lampe, Zhang, Zhu, Tzourio, Mazoyer and Joliot.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cluster analysis of the deep white matter (DWM) PVS of the ENCOD set (N = 1,782). The prediction maps were thresholded at 0.5. (A) Histogram distribution of the number of clusters per subject. (B) visual grading. (C) Number of clusters vs. visual grading (R²_0.5 = 0.45, p-Value < 10^{– 4}). (D) Summary of PVS load values within the 4 groups.