Table 2.
Meta-analysis of the studies reporting the association between over-expressed PCAT6 and clinicopathological parameters
| Clinicopathological parameters | Studies | Patients | Mode | OR (95% CI) | P value | Heterogeneity | |
|---|---|---|---|---|---|---|---|
| I2 (%) | P-value | ||||||
| Age (old vs young) | 9 | 736 | Random | 0.80 [0.51, 1.23] | 0.31 | 53 | 0.03 |
| Gender (male vs female) | 7 | 267 | Fixed | 1.84 [1.31, 2.59] | 0.0005 | 0 | 0.60 |
| Tumor size (big vs small) | 6 | 524 | Random | 2.73 [1.00, 7.44] | 0.05 | 86 | < 0.00001 |
| TNM stage (I + II VS III + IV) | 6 | 211 | Random | 0.29 [0.09, 0.94] | 0.04 | 86 | < 0.00001 |
| Differentiation (well + moderat vs poor) | 4 | 306 | Random | 1.77 [0.21, 15.11] | 0.60 | 94 | < 0.00001 |
| Metastasis (yse vs no) | 10 | 746 | Random | 5.02 [1.36, 18.57] | 0.02 | 93 | < 0.00001 |
Random Random-effects, Fixed Fixed-effects, OR Odds ratio, CI confidence interval