Fig. 6.

External validation in the eICU-CRD database. A Classification in the training dataset. The convex hulls of data points were assigned to the different clusters, and they were projected to two-dimensional space by principal component analysis. B Classification in the eICU-CRD dataset. The class membership of the new patients was determined by the highest probability predicted by the FMM. C–E Relationship between the difference between actual and optimal fluid volume and hospital mortality rate. The models were trained with quadratic terms for the difference between actual and optimal fluid volume. F The relationship between hospital mortality and the difference between actual and optimal norepinephrine dose