Fig. 5.

Significant mutations and CNVs between the TGF-β subgroups in GIAD. a, b Comparison of tumor mutation burden (TMB) and CNV burden in different TGF-β cluster. c Mutation frequency of significant mutation gene in two TGF-β subtypes in stomach adenocarcinoma (Fisher’s exact test, FDR < 0.05). d Chromosome map shows significant amplification and deletion of chromosome regions in stomach adenocarcinoma (Fisher’s exact test, FDR < 0.05); The bar plot on the right panel shows the amplification of the chromosomal region where EGFR is located. *P < 0.05, **P < 0.01, ***P < 0.001