Table 2. Brain and Blood Uptake of [¹⁸F]D15FSP,^a, [¹⁸F]D3FSP,^b and [¹⁸F]AV-45^b in CD-1 Mice (%ID/g, Avg ± SD, n = 3–6).

		time after injection (min)
organ	tracer	2	30	60	120
brain	[18F]D15FSP	5.99 ± 0.14	1.30 ± 0.19	1.11 ± 0.03	1.18 ± 0.11
	[18F]D3FSP	5.69 ± 0.31	1.66 ± 0.20	1.37 ± 0.13	1.24 ± 0.06
	[18F]AV-45	4.77 ± 0.61	1.59 ± 0.16	1.46 ± 0.16	1.38 ± 0.18
blood	[18F]D15FSP	2.21 ± 0.16	2.16 ± 0.16	1.98 ± 0.24	1.51 ± 0.28
	[18F]D3FSP	2.14 ± 0.12	1.94 ± 0.41	1.88 ± 0.17	1.47 ± 0.19
	[18F]AV-45	2.49 ± 0.29	2.71 ± 0.38	2.17 ± 0.38	1.74 ± 0.31

^aDetailed data for biodistribution of [¹⁸F]D15FSP are presented in Supporting Information (Table S1).

^bAveraged values for [¹⁸F]D3FSP and [¹⁸F]AV-45 were from previously reported data^12,17 and other in-house data.