FIGURE 1.

Survival rate of B cell activating factor belonging to the tumor necrosis factor (TNF) family‐transgenic (BAFF‐Tg) mice is significantly reduced in the two monoclonal anti‐TNF antibody groups compared to controls. Representation of the Kaplan–Meier curve of survival is shown. Mice were randomized into four groups of treatment: anti‐mouse TNF monoclonal antibody [clone TN3 19.12 (referred to as TN3) = MTX (n = 15] humanized monoclonal anti‐TNF antibody, adalimumab (referred to as ADA) = MTX (n = 13), human recombinant TNF‐R2‐Fc fragment, etanercept (referred to as ETA) = MTX (n = 15) and controls (n = 22). Survival is compared using log‐rank (Mantel–Cox) test