FIGURE 4.

CCR8 expression is dispensable for Foxp3⁺ Treg cell accumulation within tumours. (a) Representative flow cytometry (left) and replicate measurements (right) of Foxp3⁺ Treg cells within spleens and MC38 tumours of WT and Ccr8 ^−/− animals at day 21 following tumour implantation. (b) Representative flow cytometry (left) and replicate measurements (right) of CD4⁺ and CD8⁺ Tconv cells within spleens and MC38 tumours of WT and Ccr8 ^−/− animals at day 21 following tumour implantation. n = 11–18 mice per genotype. Data are representative of 4 independently repeated experiments. Bars and error represent mean and SEM. Student's t test; ns, not significant