Table 2.
Experienced post-operative outcomes, in the full study cohort and matched cohort
| Full Study Cohort | Matched Cohort | |||||
|---|---|---|---|---|---|---|
| No Protective Ventilation (n = 2,844) |
Protective Ventilation (n = 388) |
P-Value | No Protective Ventilation (n = 381) |
Protective Ventilation (n = 381) |
P-Value | |
| Postoperative Outcomes | ||||||
| 30-Day Pulmonary Complications | 362 (12.7) | 65 (16.8) | 0.028 | 59 (15.5) | 64 (16.8) | 0.615 |
| 30-Day Major Morbidity | 565 (19.9) | 94 (24.2) | 0.046 | 86 (22.6) | 93 (24.4) | 0.544 |
| 30-Day Major Morbidity and/or Mortality | 578 (20.3) | 98 (25.3) | 0.025 | 89 (23.4) | 96 (25.2) | 0.550 |
| Pulmonary Complications | ||||||
| ARDS | 9 (0.3) | 2 (0.5) | 0.632 | 0 (0.0) | 2 (0.5) | N/A |
| Air leak > 5 days | 178 (6.3) | 27 (7.0) | 0.596 | 24 (6.3) | 27 (7.1) | 0.662 |
| Atelectasis | 77 (2.7) | 22 (5.7) | 0.002 | 19 (5.0) | 21 (5.5) | 0.739 |
| Bronchopleural Fistula | 2 (0.1) | 0 (0.0) | 0.999 | 0 (0.0) | 0 (0.0) | N/A |
| Pneumonia | 62 (2.2) | 11 (2.8) | 0.415 | 11 (2.9) | 10 (2.6) | 0.827 |
| Pneumothorax | 60 (2.1) | 10 (2.6) | 0.553 | 18 (4.7) | 10 (2.6) | 0.131 |
| Other pulmonary event | 34 (1.2) | 8 (2.1) | 0.158 | 5 (1.3) | 8 (2.1) | 0.405 |
| Pulmonary embolism | 12 (0.4) | 4 (1.0) | 0.116 | 3 (0.8) | 4 (1.1) | 0.706 |
| Respiratory failure | 40 (1.4) | 9 (2.3) | 0.180 | 4 (1.1) | 8 (2.1) | 0.248 |
| Tracheostomy | 14 (0.5) | 2 (0.5) | 0.999 | 1 (0.3) | 1 (0.3) | 0.999 |
| Ventilator support > 48 hours | 7 (0.3) | 1 (0.3) | 0.999 | 1 (0.3) | 0 (0.0) | N/A |
| Morbidity Complications | ||||||
| Return to Operating Room | 0 (0.0) | 0 (0.0) | N/A | 0 (0.0) | 0 (0.0) | N/A |
| Atrial Arrhythmia | 241 (8.5) | 39 (10.1) | 0.300 | 31 (8.1) | 39 (10.2) | 0.302 |
| Ventricular Arrhythmia | 9 (0.3) | 0 (0.0) | 0.611 | 5 (1.3) | 0 (0.0) | N/A |
| Myocardial Infarction | 12 (0.4) | 2 (0.5) | 0.681 | 4 (1.1) | 2 (0.5) | 0.414 |
| Sepsis | 9 (0.3) | 1 (0.3) | 0.999 | 1 (0.3) | 1 (0.3) | 0.999 |
| Renal Failure | 9 (0.3) | 3 (0.8) | 0.167 | 1 (0.3) | 2 (0.5) | 0.564 |
| Central Neurological Event | 8 (0.3) | 1 (0.3) | 0.999 | 2 (0.5) | 1 (0.3) | 0.564 |
| Unexpected ICU Admission | 66 (2.3) | 11 (2.8) | 0.533 | 11 (2.9) | 11 (2.9) | 0.999 |
| Anastomic Leak | 0 (0.0) | 0 (0.0) | N/A | 0 (0.0) | 0 (0.0) | N/A |
| Any morbidity | 303 (10.7) | 50 (12.9) | 0.186 | 42 (11.0) | 49 (12.9) | 0.425 |
| Mortality Complications | ||||||
| 30-Day Mortality | 27 (1.0) | 6 (1.6) | 0.277 | 3 (0.8) | 5 (1.3) | 0.480 |
Data are presented as frequency (percentage) or median with 25th and 75th percentiles, as appropriate. Pre-match population comparisons calculated using Chi-Square or Fisher’s Exact tests for categorical variables, as appropriate. Matched population comparisons were calculated using McNemar tests for categorical variables.
Abbreviations: ARDS = acute respiratory distress syndrome, ICU = intensive care unit.