Table 2.

The significantly downregulated GO terms involved in adaptive immunity in Mut-10d_vs_WT-10d.

GO.ID	Term	Ontology	Significant	Annotated	P-value	Q-value
GO:0046649	lymphocyte activation	biological process	22/917	133/20731	8.80E-08	2.67E-05
GO:0042110	T cell activation	biological process	15/917	66/20731	1.40E-07	3.63E-05
GO:0050863	regulation of T cell activation	biological process	8/917	33/20731	7.40E-05	0.006453
GO:0050863	regulation of T cell activation	biological process	8/917	33/20731	7.40E-05	0.006453
GO:0050868	negative regulation of T cell activation	biological process	6/917	20/20731	0.00017	0.01143
GO:0042102	positive regulation of T cell proliferation	biological process	5/917	15/20731	0.00035	0.020149
GO:0050671	positive regulation of lymphocyte proliferation	biological process	5/917	15/20731	0.00035	0.020149
GO:0051251	positive regulation of lymphocyte activation	biological process	10/917	62/20731	0.00036	0.02059
GO:0042129	regulation of T cell proliferation	biological process	6/917	23/20731	0.00039	0.02147
GO:0050670	regulation of lymphocyte proliferation	biological process	6/917	23/20731	0.00039	0.02147
GO:0031294	lymphocyte costimulation	biological process	4/917	9/20731	0.0004	0.021483
GO:0050870	positive regulation of T cell activation	biological process	5/917	16/20731	0.00049	0.024804
GO:0031295	T cell costimulation	biological process	4/917	9/20731	0.0004	0.021482
GO:0042098	T cell proliferation	biological process	6/917	24/20731	0.0005	0.025023
GO:0048534	hematopoietic or lymphoid organ development	biological process	35/917	438/20731	0.00057	0.027892
GO:0046651	lymphocyte proliferation	biological process	6/917	27/20731	0.00098	0.040909