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Two-component system of C. albicans and its downstream pathways. Seven proteins of the two-component system in C. albicans are shown, including three hybrid HPKs (Sln1p, Nik1p/Cos1p, Chk1p), three RRs (Ssk1p, Skn7p, Crr1p/Srr1p), and one intermediate transfer protein (Ypd1p). The downstream responses of two-component system are complex and diverse, which is highly related to morphogenesis, oxidative and osmotic stress, quorum sensing, virulence regulation and so on
