Table 3.

Medication use and clinical data (Dutch cohort) for remission and active samples (n = 44). T1 = time point 1, T2 = time point 2. Continuous variables are expressed as median (interquartile range, IQR), the other variables (distribution and medications use) are shown as n and percentage. L1 = ileal, L2 = colonic, L3 = ileo-colonic distribution of CD. CRP = C-reactive protein. * use of antibiotics in the 2 months prior collection of the sample

	T1 Remission (n = 22)	T2 Remission (n = 12)	T2 Active (n = 10)
Distribution	L1 = 10 (45.4%) L2 = 5 (22.7%) L3 = 7 (31.8%)	L1 = 5 (41.67%) L2 = 2 (16.67%) L3 = 5 (41.67%)	L1 = 5 (50%) L2 = 3 (30%) L3 = 2 (20%)
Fecal calprotectin (μg/g) (median, IQR)	43 (45.5)	38.5 (62.5)	252 (80)
Serum CRP	1.9 (1.75)	1.5 (1.3)	3.5 (2.8)
Medications
Mesalamine	n = 4 (18.2%)	n = 1 (8.33%)	n = 1 (10%)
Immunosuppressants	n = 9 (40.9%)	n = 5 (41.67%)	n = 5 (50%)
Biologics	n = 13 (59.1%)	n = 5 (41.67%)	n = 8 (80%)
Proton pump inhibitor	n = 8 (36.4%)	n = 4 (33.33%)	n = 4 (40%)
Antibiotics*	n = 1 (4.5%)	n = 1 (8.33%)	n = 0