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. 2021 Jun 23;11:634841. doi: 10.3389/fonc.2021.634841

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Copyright © 2021 Xue, Wang, Xie, Yang, Gong, Guan, Wei, Zhu and Niu

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of correlation between signature and TMB levels and immune checkpoints. (A) The 18-miRNA-based signature has a strong positive correlation with TMB levels. (B) The 18-miRNA-based signature has a weak positive correlation with CTLA4. (C) The 18-miRNA-based signature has a weak positive correlation with CD274 (PDL-1). (D) The 18-miRNA-based signature has no correlation with SNCA (PD-1).