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. 2021 Jul 12;95(15):e00495-21. doi: 10.1128/JVI.00495-21

FIG 4.

FIG 4

MMLV p12-PM14 mutant DNAs are poorly expressed and show decreased association with RNA polymerase II. (A) Flow cytometry analysis of HeLa cells infected with VSV-G pseudotyped WT or p12-m14 mutant MMLV-GFP viruses at 1 d postinfection. FSC, forward scatter. A representative experiment is shown. (B) RNA polymerase II ChIP analysis of chromatin harvested at 2 days following WT or p12-PM14 mutant MMLV-GFP infection of HeLa cells. ChIP data are presented as percentage of input DNA (means ± SEs from three independent experiments). Student’s t test was used for statistical analysis. *, P < 0.05 compared to WT virus.