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D5 and D5_AR neutralize HIV-1 in vitro in a size-independent manner. scFv, Fab, and IgG constructs of D5 (A) and D5_AR (B) are similarly effective in vitro at neutralizing lentivirus pseudotyped with HIV-1 HXB2. Data points and error bars are the mean percent infections and standard errors of the means, respectively (n = 2). Antibody construct images used in this figure were generated with BioRender.
