TABLE 2.

Effect of SL1 nucleotide mutations on RNA-nsP1 binding kinetics^a

Type of RNA	Apparent Kd (μM)
WT	0.42 ± 0.03
Linear	7.53 ± 2.3
TC-83	4.14 ± 1.6
CM1	2.69 ± 0.7
CM2	3.03 ± 0.7
TC-83CM	2.88 ± 0.8

^aKinetic parameters were calculated using the SigmaPlot program. Values are expressed as mean ± standard deviation with an R² value of ≥0.95.