TABLE 1.

Quantification of RNA expression for known anti-HIV factors induced by the different subtypes of IFN-α

Factor	Fold change in factor RNA expression vs untreateda
	IFN-α1	IFN-α2	IFN-α4	IFN-α5	IFN-α6	IFN-α7	IFN-α8	IFN-α10	IFN-α14	IFN-α16	IFN-α17	IFN-α21
IFITM1	6.4	9.4	7.0	8.0	8.0	8.0	7.4	8.0	10.6	9.4	9.3	6.7
IFITM2	0.4	4.5	4.3	0.4	5.6	2.3	27.1	3.0	0.6	0.6	0.3	0.3
IFITM3	1.9	2.8	2.2	3.0	3.6	3.2	4.2	1.9	3.4	3.1	2.4	2.1
CH25H	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND	ND
TRIM5α	2.3	2.6	2.2	2.6	2.8	2.6	3.1	2.6	3.5	2.8	2.5	2.2
SAMHD1	1.2	1.4	1.4	1.5	1.5	1.6	1.9	1.7	1.8	1.5	1.3	1.5
Mx2	1.3	3.3	2.5	2.0	2.4	1.7	3.7	2.1	5.1	2.4	2.0	1.2
TRIM22	3.4	4.9	4.0	4.6	4.5	3.9	5.8	4.2	5.9	4.7	4.2	3.5
SLFN11	1.4	1.3	1.3	1.1	1.3	1.0	1.1	1.1	1.3	1.4	1.0	1.2
ISG15	29.3	49.9	40.0	42.5	48.8	45.4	83.7	48.1	83.0	55.6	59.5	35.2
BST2	2.0	2.5	2.2	2.3	2.5	2.2	3.0	2.7	3.2	2.9	2.5	2.3
APOBEC3G	1.4	1.5	1.3	1.2	1.2	1.2	1.2	1.1	1.4	1.4	1.3	1.1
GBP2	1.3	1.6	1.0	1.4	1.6	1.5	1.8	2.4	2.3	1.4	1.3	1.2
GBP5	1.1	1.0	1.1	1.5	1.4	1.9	1.8	1.0	1.7	1.1	1.1	1.0
90K	9.7	14.2	4.5	14.5	11.3	26.1	17.5	4.4	8.4	20.0	14.3	6.0
MARCH8	0.9	0.8	0.8	1.1	1.2	0.7	1.0	1.0	0.9	1.0	1.0	0.9
SERINC3	1.0	0.8	0.9	0.8	0.8	0.8	0.7	0.9	0.8	0.8	0.7	0.8
SERINC5	0.8	1.2	1.2	1.3	1.5	1.2	1.9	0.8	1.3	0.9	0.7	1.0

^aND, not determined.