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. 2021 May 24;105(1):181–187. doi: 10.4269/ajtmh.21-0045

Table 2.

Serological results obtained, including post-surgical patients without abdominal cystic echinococcosis as controls

VIRapid® test, Lima VIRapid test, Pavia* (weak bands considered positive) VIRapid test, Pavia* (weak bands considered negative) ELISA RIDASCREEN test, Pavia
Performance (95% CI) CE pos CE neg Total Performance (95% CI) CE pos CE neg Total Performance (95% CI) CE pos CE neg Total Performance (95% CI) CE pos CE neg Total
Test pos 25 17 42 Test pos 24 37 61 Test pos 22 21 43 Test pos 18 23 41
Test neg 8 64 72 Test neg 9 43 52 Test neg 11 59 70 Test neg 9 51 60
Total 33 81 114 Total 33 80 113 Total 33 80 113 Total 27 74 101
Sensitivity 0.76 (0.67–0.83) Sensitivity 0.73 (0.63–0.81) Sensitivity 0.67 (0.57-0.75) Sensitivity 0.67 (0.57–0.76)
Specificity 0.79 (0.69–0.85) Specificity 0.54 (0.43–0.62) Specificity 0.74 (0.63–0.80) Specificity 0.69 (0.57–0.76)
PPV 0.59 (0.48–0.67) PPV 0.39 (0.30–0.48) PPV 0.51 (0.41–0.60) PPV 0.44 (0.33–0.53)
NPV 0.89 (0.81–0.94) NPV 0.83 (0.74–0.89) NPV 0.84 (0.76–0.90) NPV 0.85 (0.76–0.91)
LR+ 3.61 (2.72–4.27) LR+ 1.57 (0.14–2.06) LR+ 2.54 (1.84–3.20) LR+ 2.15 (1.51–2.80)
LR– 0.31 (0.25–0.39) LR– 0.51 (0.39–0.70) LR– 0.46 (0.35–0.61) LR– 0.48 (0.36–0.67)

CE = cystic echinococcosis; neg = negative; LR– = negative likelihood ratio; LR+ = positive likelihood ratio; NPV = negative predictive value; pos = positive; PPV = positive predictive value.

*

One serum from one post-surgical case with no abdominal cystic echinococcosis cyst at the time of screening was not available for analysis in Pavia.

Sera from three uninfected, four post-surgical, and six cystic echinococcosis (CE)-infected individuals (three CE stage 1, 1 one CE stage 3a, one CE stage 3b, and one CE stage 5) were not available for testing.