Table 2.
Serological results obtained, including post-surgical patients without abdominal cystic echinococcosis as controls
| VIRapid® test, Lima | VIRapid test, Pavia* (weak bands considered positive) | VIRapid test, Pavia* (weak bands considered negative) | ELISA RIDASCREEN test, Pavia‡ | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Performance (95% CI) | CE pos | CE neg | Total | Performance (95% CI) | CE pos | CE neg | Total | Performance (95% CI) | CE pos | CE neg | Total | Performance (95% CI) | CE pos | CE neg | Total | 
| Test pos | 25 | 17 | 42 | Test pos | 24 | 37 | 61 | Test pos | 22 | 21 | 43 | Test pos | 18 | 23 | 41 | 
| Test neg | 8 | 64 | 72 | Test neg | 9 | 43 | 52 | Test neg | 11 | 59 | 70 | Test neg | 9 | 51 | 60 | 
| Total | 33 | 81 | 114 | Total | 33 | 80 | 113 | Total | 33 | 80 | 113 | Total | 27 | 74 | 101 | 
| Sensitivity | 0.76 (0.67–0.83) | Sensitivity | 0.73 (0.63–0.81) | Sensitivity | 0.67 (0.57-0.75) | Sensitivity | 0.67 (0.57–0.76) | ||||||||
| Specificity | 0.79 (0.69–0.85) | Specificity | 0.54 (0.43–0.62) | Specificity | 0.74 (0.63–0.80) | Specificity | 0.69 (0.57–0.76) | ||||||||
| PPV | 0.59 (0.48–0.67) | PPV | 0.39 (0.30–0.48) | PPV | 0.51 (0.41–0.60) | PPV | 0.44 (0.33–0.53) | ||||||||
| NPV | 0.89 (0.81–0.94) | NPV | 0.83 (0.74–0.89) | NPV | 0.84 (0.76–0.90) | NPV | 0.85 (0.76–0.91) | ||||||||
| LR+ | 3.61 (2.72–4.27) | LR+ | 1.57 (0.14–2.06) | LR+ | 2.54 (1.84–3.20) | LR+ | 2.15 (1.51–2.80) | ||||||||
| LR– | 0.31 (0.25–0.39) | LR– | 0.51 (0.39–0.70) | LR– | 0.46 (0.35–0.61) | LR– | 0.48 (0.36–0.67) | ||||||||
CE = cystic echinococcosis; neg = negative; LR– = negative likelihood ratio; LR+ = positive likelihood ratio; NPV = negative predictive value; pos = positive; PPV = positive predictive value.
One serum from one post-surgical case with no abdominal cystic echinococcosis cyst at the time of screening was not available for analysis in Pavia.
Sera from three uninfected, four post-surgical, and six cystic echinococcosis (CE)-infected individuals (three CE stage 1, 1 one CE stage 3a, one CE stage 3b, and one CE stage 5) were not available for testing.