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. Author manuscript; available in PMC: 2021 Jul 12.
Published in final edited form as: J Physiol. 2021 Feb 4;599(5):1487–1511. doi: 10.1113/JP280034

Table 2.

Metabolites showing a significant treatment and or a sex effect in HFCS exposed animals

6 weeks
30 weeks
Total no. of biochemicals Biochemicals Total no. of biochemicals Biochemicals

Female 187 59↑ 128↓ 23 9↑ 14↓
Male 140 71↑ 69↓ 30 26↑ 4↓
Number of biochemicals
Sugar effect 202 52
Sex effect 159 145
Sugar × Sex interaction 87 27

Significance determined by two-way ANOVA, where sex and treatment were factors and corrected for multiple testing using the FDR. N = 8 per group.