Table 9.
Fold change in oxidative stress metabolites in HFCS-exposed 6-week-old animals
| Female | q value | Male | q value | |
|---|---|---|---|---|
| Glutathione (reduced) | 13.54 | 0.0004 | 1.57 | 0.154 |
| Glutathione (oxidized) | 0.91 | 0.091 | 0.62 | 6.02 E-05 |
| Methionine | 0.82 | 7.09 E-05 | 0.91 | 0.031 |
| Homocysteine | 1.39 | 0.12 | 1.67 | 0.018 |
| 5-Methyltetrahydrofolate | 4.10 | 2.47 E-07 | 1.85 | 0.005 |
| 2-Aminobutyrate | 2.86 | 1.74 E-09 | 3.69 | 2.10 E-10 |
| Ophthalmate | 5.32 | 5.35 E-07 | 5.82 | 1.42 E-06 |
| Hypotaurine | 0.48 | 2.79 E-05 | 0.38 | 3.30 E-06 |
| Taurine | 0.77 | 0.008 | 0.82 | 0.07 |
| Ascorbate | 1.84 | 2.95 E-05 | 1.29 | 0.03 |
Significance determined by two-way ANOVA, where sex and treatment were factors and corrected for multiple testing using the FDR. N = 8 per group.