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. 2021 Jul 5;14:2955–2962. doi: 10.2147/JIR.S310116

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© 2021 Zhang et al.

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Calcitriol could inhibit HS-induced pyroptosis in human corneal epithelial cells. (A) Calcitriol treatment (10⁻⁶M) suppressed LDH release in HS-stimulated iHCECs. (B) Scanning electron micrographs of iHCECs from blank, HS, and calcitriol treated groups at ×25,000 magnification. Scale=5 μm. (C) Calcitriol treatment (10⁻⁶M) reduced the proportion of pyroptotic cells, shown as Caspase- 1/PI double positive by flow cytometry. *P<0.05, **P<0.01.