Table 3. Association of IL-13 genetic polymorphisms with study factorsa.
| Factor | IL13-1055 (N = 71) | IL13-591 (N = 71) | IL13-1258 (N = 71) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| C/C | C/T | T/T | A/A | A/G | G/G | A/A | A/G | G/G | |
| Age in years [n (%)] | |||||||||
| ≤11 | 8 (11.27) | 8 (11.27) | 2 (2.81) | 12 (16.90) | 21 (29.58) | 6 (8.45) | 8 (11.27) | 18 (25.35) | 5 (7.04) |
| 12–14 | 14 (19.71) | 11 (15.49) | 4 (5.63) | 17 (23.94) | 10 (14.08) | 3 (4.23) | 15 (21.12) | 12 (16.90) | 4 (5.63) |
| 15+ | 8 (11.27) | 13 (18.31) | 3 (4.23) | 1 (1.41) | 1 (1.41) | 0 (0.00) | 7 (9.86) | 2 (2.82) | 0 (0.00) |
| p-val | 0.817 | 0.291 | 0.065 (p-val (trends) = 0.008) | ||||||
| Gender | |||||||||
| Male | 13 (18.31) | 15 (21.13) | 8 (11.27) | 19 (26.76) | 15 (21.13) | 2 (2.82) | 17 (23.94) | 15 (21.13) | 4 (5.63) |
| Female | 11 (15.49) | 14 (19.72) | 10 (14.08) | 20 (28.17) | 15 (21.13) | 0 (0.00) | 15 (21.13) | 17 (23.94) | 5 (7.04) |
| p-val | 0.815 | 0.366 | 0.841 | ||||||
| S. haematobium | |||||||||
| infected | 10 (14.08) | 15 (21.13) | 5 (7.04) | 15 (21.13) | 14 (19.72) | 1 (1.41) | 9 (12.68) | 15 (21.13) | 6 (8.45) |
| uninfected | 14 (19.72) | 14 (19.72) | 13 (18.31) | 24 (33.80) | 16 (22.54) | 1 (1.41) | 23 (32.39) | 17 (23.94) | 3 (4.23) |
| p-val | 0.27 | 0.772 | 0.078 (p-val (trends) = 0.025) | ||||||
| Soil-transmitted Helminthsc | |||||||||
| infected | 5 (7.04) | 5 (7.04) | 1 (1.41) | 7 (9.86) | 4 (5.63) | 0 (0.00) | 5 (7.04) | 3 (4.23) | 3 (4.23) |
| uninfected | 19 (26.76) | 24 (33.80) | 17 (23.94) | 32 (45.07) | 26 (36.62) | 2 (2.82) | 27 (38.03) | 29 (40.85) | 6 (8.45) |
| p-val | 0.378 | 0.721 | 0.206 | ||||||
Comparisons between participants with the various groups were conducted using the χ2 tests.
a The pooled data was used in the analyses (i.e. where N = 71)
b Number of participants in the group of interest (percent prevalence or percent frequency)
cSoil-transmitted Helminths represent Ascaris lumbricoides, and Hookworm (Ancylostoma duodenale, Necator americanus).