Table 3. Toxicity of insecticides that target the VSSC against susceptible (ROCK) and resistant (1534C:ROCK, KDR:ROCK and LKR) strains of A. aegypti.
| Insecticide¥ | Strain | LD50* (95% CI) | Slope (±SEM) | n |
|---|---|---|---|---|
| 1R-cis-αS cypermethrin | ROCK | 0.008 (0.007–0.008) | 3.0 (0.2) | 680 |
| 1534C:ROCK | 0.088 (0.072–0.107) | 2.3 (0.2) | 506 | |
| KDR:ROCK | 0.12 (0.10–0.15) | 2.1 (0.3) | 520 | |
| LKR | 0.19 (0.15–0.23) | 1.2 (0.1) | 884 | |
| 1R-trans fenfluthrin | ROCK | 0.63 (0.53–0.75) | 2.8 (0.3) | 880 |
| LKR | 11.1 (8.38–14.9) | 1.8 (0.3) | 600 | |
| 1R-trans tefluthrin | ROCK | 0.67 (0.65–0.70) | 4.5 (0.1) | 540 |
| KDR:ROCK | 26.9 (25.8–28.2) | 1.3 (0.1) | 720 | |
| LKR | 1.87 (1.55–2.27) | 1.3 (0.1) | 680 | |
| alpha-cypermethrin | ROCK | 0.032 (0.027–0.039) | 3.5 (0.6) | 817 |
| 1534C:ROCK | 0.43 (0.376–0.49) | 2.5 (0.2) | 578 | |
| KDR:ROCK | 0.53 (0.44–0.63) | 1.8 (0.1) | 712 | |
| alpha-cypermethrin | ROCK | 0.048 (0.043–0.053) | 2.7 (0.2) | 520 |
| LKR | 0.19 (0.13–0.29) | 1.1 (0.1) | 740 | |
| bioallethrin | ROCK | 3.85 (3.61–4.11) | 4.2 (0.2) | 620 |
| LKR | 21.9 (19.0–25.2) | 2.7 (0.2) | 420 | |
| bioresmethrin | ROCK | 0.43 (0.392–0.472) | 4.8 (0.4) | 520 |
| LKR | 4.54 (3.48–5.94) | 1.0 (0.1) | 820 | |
| cis-permethrin | ROCK | 0.55 (0.54–0.57) | 3.8 (0.1) | 620 |
| 1534C:ROCK | 4.96 (4.07–6.05) | 2.2 (0.3) | 689 | |
| cis-permethrin | ROCK | 0.70 (0.64–0.76) | 1.5 (0.1) | 480 |
| LKR | 4.78 (4.06–5.64) | 1.4 (0.1) | 800 | |
| cyfluthrin | ROCK | 0.023 (0.019–0.029) | 2.1 (0.2) | 640 |
| LKR | 0.51 (0.38–0.69) | 1.01 (0.1) | 1100 | |
| cyhalothrin | ROCK | 0.025 (0.023–0.026) | 3.7 (0.2) | 840 |
| LKR | 0.25 (0.21–0.32) | 1.4 (0.1) | 760 | |
| LKR x ROCK F1 | 0.050 (0.042–0.060) | 2.2 (0.2) | 620 | |
| cypermethrin | ROCK | 0.075 (0.066–0.084) | 3.2 (0.3) | 837 |
| LKR | 0.61 (0.50–0.74) | 1.4 (0.1) | 940 | |
| deltamethrin | ROCK | 0.005 (0.004–0.006) | 2.4 (0.4) | 615 |
| LKR | 0.21 (0.18–0.25) | 1.1 (0.1) | 820 | |
| etofenprox | ROCK | 2.94 (2.85–3.04) | 4.6 (0.1) | 712 |
| LKR | 42.2 (24.9–71.3) | 1.2 (0.3) | 700 | |
| flumethrin | ROCK | 0.70 (0.59–0.83) | 2.7 (0.3) | 620 |
| LKR | 39.7 (28.3–55.8) | 0.7 (0.1) | 1040 | |
| permethrin | ROCK | 0.23 (0.23–0.24) | 3.6 (0.04) | 800 |
| LKR | 1.30 (0.94–1.81) | 1.15 (0.09) | 814 | |
| KDR:ROCK | 12.1 (10.2–14.3) | 4.4 (0.3) | 660 | |
| KDR:ROCK x LKR F1 | 10.5 (9.01–12.3) | 2.2 (0.2) | 520 | |
| tau-fluvalinate | ROCK | 0.69 (0.59–0.82) | 3.2 (0.5) | 440 |
| LKR | 4.99 (3.94–6.34) | 1.1 (0.1) | 880 | |
| tefluthrin | ROCK | 4.97 (4.62–5.33) | 4.2 (0.3) | 540 |
| LKR | 25.2 (19.5–32.5) | 2.1 (0.4) | 720 | |
| transfluthrin | ROCK | 0.63 (0.60–0.66) | 4.8 (0.2) | 520 |
| LKR | 3.83 (3.17–4.63) | 1.6 (0.1) | 540 | |
| KDR:ROCK | 14.8 (13.8–15.8) | 3.1 (0.2) | 520 | |
| KDR:ROCK x LKR F1 | 11.3 (9.37–13.6) | 2.0 (0.2) | 571 | |
| trans-permethrin | ROCK | 0.45 (0.41–0.49) | 3.8 (0.3) | 513 |
| 1534C:ROCK | 4.45 (3.79–5.21) | 3.2 (0.2) | 520 | |
| trans-permethrin | ROCK | 0.57 (0.48–0.67) | 3.7 (0.5) | 900 |
| LKR | 6.22 (4.37–8.86) | 1.0 (0.1) | 520 | |
| DCJW | ROCK | 1.84 (1.72–1.96) | 4.0 (0.2) | 720 |
| LKR | 11.3 (9.63–13.3) | 1.9 (0.2) | 727 | |
| DDT | ROCK | 15.7 (15.2–16.3) | 3.8 (0.1) | 640 |
| LKR | 118 (96.7–144) | 1.4 (0.1) | 994 |
¥Bioassays done with the same insecticide solutions for different strains share the same insecticide name.
*LD50, ng/mosquito.