. Author manuscript; available in PMC: 2021 Jul 12.

Published in final edited form as: J Pathol. 2019 Dec 3;250(2):205–216. doi: 10.1002/path.5361

Table 3.

Cox hazard ratio of mesothelioma patients

	Hazard ratio	95% CI
		Min	Max	P value
CD27⁺ TILs (15≥/HPF)	0.48	0.25	0.96	0.037
Tumour CD70 expression	2.25	1.21	4.17	0.010
FOXP3⁺ TILs (19≥/HPF)	2.81	1.39	5.66	0.004
CD3⁺ TILs (3≥/HPF)	6.12	2.64	14.2	<0.001

Cox proportional hazards regression analysis was performed to analyse the association of survival and other factors. The initial model included age, sex, tumour histology, and data from immunohistochemical staining for CD70, CD27, CD3, CD4, CD8, CD56, PDCD1, and FOXP3 expression in tumours or TILs. A backward elimination with a threshold of p =0.05 was used to select variables in the final model. TILs, tumour-infiltrating lymphocytes; HPF, high-power field (×400).