Table 3.

Adverse events

Adverse event	Carrageenan (n = 141)	Placebo (n = 139)	pa
Any	62 (44.0%)	43 (30.9%)	0.02
Unusually painful or heavy period	0	3 (2.2%)	0.08
Vaginal bleeding in between menstrual periods	3 (2.1%)	4 (2.9%)	0.69
Pain during vaginal sex	8 (5.7%)	2 (1.4%)	0.06
Unusual vaginal discharge	8 (5.7%)	2 (1.4%)	0.06
Itching, burning or pain in genital area	16 (11.3%)	11 (7.9%)	0.33
Genital sore/ulcer	1 (0.7%)	2 (1.4%)	0.55
Needing to urinate more often than usual	1 (0.7%)	3 (2.2%)	0.31
Pain while urinating	4 (2.8%)	1 (0.7%)	0.18
Blood in urine	3 (2.1%)	1 (0.7%)	0.32
Lower abdominal pain	2 (1.4%)	0	0.16
Lower back pain	0	0	—
Other	16 (11.3%)	14 (10.1%)	0.73

^aBy z test.