Table 1.

Genetic variants found in R4 cells

Gene	Variant	Variant location	Consequence/type	Total read depth	Variant freq	SIFT/PolyPhen	COSMIC ID/dbSNP
SETD2	chr3:47162614G > T p.T1171K c.3512C > A	exon 3	Missense substitution	266	22%	deleterious(0) probably_damaging (0.98)	—
EGFR	chr7:55211142A > G p.K129E c.385A > G	exon 3	Missense substitution	314	16%	tolerated(1) benign(0.005)	COSM 5041204
FANCC	chr9:97864140C > A c.1534 + 8G > T	exon 15	Splice region	126	10%	—	—