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Pharmacokinetic parameters of 12.
| parameters | Mean ± SD (n = 2) |
|
|---|---|---|
| iv (1 mg/kg)a | ig (5 mg/kg)b | |
| Tmax (h) | / | 2 ± 0 |
| Cmax (ng/ml) | / | 19 ± 9 |
| AUC0→t (h·ng/ml) | 47.2 ± 1.8 | 48.3 ± 28 |
| AUC0→∞ (h·ng/ml) | 49.8 ± 1.5 | / |
| MRTINF (h) | 1.46 ± 0.027 | / |
| T1/2 (h) | 1.21 ± 0.14 | / |
| F (%) | / | 20.4 ± 11.9 |
iv means intravenous injection.
ig means intragastrical administration.
